Matthew K Topham Selected Research

Diacylglycerol Kinase

1/2022	Downregulation of Diacylglycerol Kinase Delta Contributes to Hyperglycemia-Induced Insulin Resistance.
1/2018	Deletion of diacylglycerol kinase ε confers susceptibility to obesity via reduced lipolytic activity in murine adipocytes.
4/2011	Endocannabinoids and diacylglycerol kinase activity.
2/2008	Downregulation of diacylglycerol kinase delta contributes to hyperglycemia-induced insulin resistance.
1/2006	The retinoblastoma family proteins bind to and activate diacylglycerol kinase zeta.

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Matthew K Topham Research Topics

Disease

8	Neoplasms (Cancer) 03/2016 - 01/2006
4	Carcinogenesis 02/2015 - 01/2009
3	Obesity 01/2020 - 02/2008
2	Insulin Resistance 01/2022 - 02/2008
2	Hyperglycemia 01/2022 - 02/2008
2	Inflammation (Inflammations) 02/2015 - 05/2013
2	Seizures (Absence Seizure) 07/2013 - 08/2012
1	Adenomatous Polyposis Coli (Familial Adenomatous Polyposis) 03/2016
1	Adenoma (Adenomas) 03/2016
1	Acne Vulgaris 03/2016
1	Exanthema (Rash) 03/2016
1	Polyps 03/2016
1	Hypoxia (Hypoxemia) 08/2013
1	Colonic Neoplasms (Colon Cancer) 05/2013
1	Intestinal Polyposis (Polyposis, Intestinal) 05/2013
1	Ischemia 08/2012
1	Epilepsy (Aura) 04/2011
1	Prostatic Neoplasms (Prostate Cancer) 04/2010
1	Breast Neoplasms (Breast Cancer) 04/2010
1	Type 2 Diabetes Mellitus (MODY) 02/2008
1	Retinoblastoma (Glioblastoma, Retinal) 01/2006

Drug/Important Bio-Agent (IBA)

5	Diacylglycerol KinaseIBA 01/2022 - 01/2006
3	Proteins (Proteins, Gene)FDA Link 07/2013 - 01/2006
3	EnzymesIBA 05/2013 - 04/2010
2	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 02/2008
2	Kainic Acid (Kainate)IBA 07/2013 - 08/2012
2	ErbB Receptors (EGF Receptor)IBA 03/2010 - 01/2009
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2009 - 09/2007
1	Sulindac (Copal)FDA LinkGeneric 03/2016
1	SaltsIBA 03/2016
1	Erlotinib Hydrochloride (CP 358,774)FDA Link 03/2016
1	Transcription Factors (Transcription Factor)IBA 02/2015
1	5' Untranslated Regions (5' UTR)IBA 08/2013
1	Phospholipids (Phosphatides)FDA LinkGeneric 05/2013
1	Platelet Activating FactorIBA 05/2013
1	Glycerophospholipids (Phosphoglycerides)IBA 05/2013
1	Phospholipases A2 (Phospholipase A2)IBA 05/2013
1	Nuclear Localization Signals (Nuclear Localization Signal)IBA 08/2012
1	EndocannabinoidsIBA 04/2011
1	1-stearoyl-2-arachidonoylglycerolIBA 04/2011
1	Glycerol (Glycerine)FDA LinkGeneric 04/2011
1	Ligases (Synthetase)IBA 04/2010
1	Androgen Receptors (Androgen Receptor)IBA 04/2010
1	Messenger RNA (mRNA)IBA 04/2010
1	Fatty Acids (Saturated Fatty Acids)IBA 04/2010
1	Gonadal Steroid Hormones (Sex Hormones)IBA 04/2010
1	Acyl Coenzyme A (Acyl CoA)IBA 04/2010
1	Fatty Acid Synthases (Fatty Acid Synthase)IBA 04/2010
1	Estrogen Receptor alphaIBA 04/2010
1	LipidsIBA 04/2010
1	triacsin CIBA 04/2010
1	CarcinogensIBA 01/2009
1	AzoxymethaneIBA 01/2009
1	DiglyceridesIBA 02/2008
1	Insulin (Novolin)FDA Link 02/2008
1	Retinoblastoma ProteinIBA 01/2006

Therapy/Procedure

1	Chemoprevention 03/2016
1	Therapeutics 01/2013